Evotec Reports Positive Top-Line Results in Phase II Study with EVT 201 in Elderly Insomniacs with Daytime Sleepiness
ثبت نشده
چکیده
Significant improvements were also seen across key PSG-derived secondary endpoints including Wake After Sleep Onset (WASO) and Latency to Persistent Sleep (LPS). Although the study was not powered to show this, the 2.5 mg dose also showed a significant effect on TWT (Total Wake Time) during the second half of the night, indicating that EVT 201 is highly effective in maintaining sleep throughout the night. This was further confirmed by the hour-by-hour analysis of TWT. Treatment with EVT 201 produced a statistically significant reduction in TWT for all hours of the night apart from hour 7.
منابع مشابه
The Relationships Between Daily Sleepiness and Cardiovascular Health Indicators in the Older Adults
Objectives: Cardiovascilar disesases and sleep disorders are two major health problems common in old age. The aim of the present study was to examine the relationship between daytime sleepiness and cardiovascular indices among Iranian older adults. Methods & Materials: A cross-sectional design was used. The sample included 321 older adults who were selected from primary healthcare centers in K...
متن کاملارزیابی یافته‌های پلی سومنوگرافی در بیماران مبتلا به آپنه انسدادی حین خواب با و بدون خواب آلودگی طی روز
Introduction: Obstructive sleep apnea syndrome(OSAS) is a common disorder in the general population. Excessive daytime sleepiness (EDS) is a frequent symptom in patients with OSA. Obstructive sleep apnea and its resultant EDS lead to an increased risk of deadly motor vehicle accidents. In this study the relationship between EDS and different polysomnographic variables in patients sufferinf from...
متن کاملبررسی میزان خواب آلودگی دانشجویان پزشکی، داشگاه علوم پزشکی مازندران، سال 1382
Background and purpose: Sleepiness is a major public health problem. Several reasons such as shift work, long time studying, etc, are the cause of sleepiness in medical students, which affect their academic performance .The aim of this study was to assess the level of daytime sleepiness in medical students. Materials and methods : Â descriptive study designed to evaluate the daytime sleepi...
متن کاملبررسی فراوانی خواب آلودگی روزانه در زنان مبتلا به فشار خون بالا
Introduction & Objective:Poor sleep quality and sleep deprivation leads to daytime sleepiness .several study showed that sleepiness related sleep deprivation may be associated with increased risk of hypertension and decrease quality of life. The aim of this study was to evaluate frequency of daytime sleepiness in hypertensive women. Materials & Methods:This is a descriptive – analytical study ...
متن کاملخوابآلودگی روزانه: عاملی مرتبط با سلامت روان سالمندان؟
Objectives: Increased Population Of Older People In Recent Decades Has Brought Their Health Issues At Forefront. Mental Health And Sleep Problems Are Common In Elderly. This Study Intended To Investigate On The Relations Between These Two. Methods & Materials: The Present Study Is A Cross-Sectional, Descriptive- Analytic One Which Has Been Implemented On Retired Elderly, Presenting At The Re...
متن کامل